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High Resolution Imaging of DNA
DNA Protein Interactions
Underlying Computational Methods
Antimicrobial Mechanisms of Action
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Single molecule biophysics of DNA

Home
Research
Research Summary
High Resolution Imaging of DNA
DNA Protein Interactions
Underlying Computational Methods
Antimicrobial Mechanisms of Action
TopoStats
People
Lab Members
Alice Pyne
Collaborators
Previous Lab Members
Work with us
Current Opportunities
Royce Schemes
Publications
News
25 March 2026
Nano Characterisation
New Nature Paper on CRISPR/Cas9!
New Nature Paper on CRISPR/Cas9!
1 December 2025
Nano Characterisation
SPM4.0 midterm meeting and first training ...
SPM4.0 midterm meeting and first training workshop held in Berlin
1 October 2025
Nano Characterisation
Sheffield hosts AFMBioMed Summer School
Sheffield hosts AFMBioMed Summer School
18 September 2025
Nano Characterisation
Paper on R-Loop formation and structure ...
Paper on R-Loop formation and structure published in PNAS
28 March 2025
Nano Characterisation
Physics of Life 2025
Physics of Life 2025
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7 February 2018

New paper published in ACS Synthetic Biology (February 2018)

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7 February 2018
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DNA Origami Inside-Out Virus

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8 January 2018

Alice has been awarded a prestigious MRC/UKRI Innovation Fellowship (Jan 2018)

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8 January 2018
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This exciting new fellowship aims to create the future for international leaders in research.

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4 December 2017

Alice is featured in UCL's recent spotlight (Dec 2017)

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4 December 2017
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Read the spotlight on Dr Alice Pyne here.

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2 October 2017

Isabel was on Sky News discussing the importance of new antibiotics (October 2017)

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2 October 2017
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2 November 2016

Alice featured in a high-profile webinar (Nov 2016)

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2 November 2016
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Alice has featured in a high-profile webinar celebrating the 30th anniversary of the Nobel Prize in Scanning Tunnelling Microscopy (STM) and the 30th anniversary since the first paper in Atomic Force Microscopy (AFM)

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1 September 2016

New paper published in Chemical Communications (Sept 2016)

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1 September 2016
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Studies of G- Quadruplexes formed within self assembled DNA mini-circles.

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Department of Materials Science & Engineering, University of Sheffield, Sir Robert Hadfield Building, Mappin Street, Sheffield, England, S1 3JD, United Kingdoma.l.pyne@sheffield.ac.uk