We are delighted to reveal that Laura has won the Open Research award for the development of CellPhe, a user-friendly free open research tool to help better understand cell mutation and resistance in cancer. This award recognises the overall impact of CellPhe as open-source software in the field of biology and the bright future ahead for automation in microscopical data analysis, as well as the undeniable hard work of the CellPhe team!
Read more about CellPhe here
We are incredibly pleased to announce that Sylvia and Libby from our lab won the first and third poster prizes, respectively, at the AFM & SPM Meeting in Durham, March 2024. Thank you for to the organisers for such a wonderful event, and this was the cherry on the cake! We had a truly brilliant time at this event, meeting fellow microscopists and exchanging research. We look forward to future events!
We are pleased to announce that our team won the award for Open Research 2023! We won this award for our work on TopoStats, which is an open source software tool used to automate editing, analysis and quantification of data obtained from Atomic Force Microscopy. The aim of our software is to aid the field in moving away from manual analysis processes which have low throughput and rely on experience researchers. Our current focus is on developing new image analysis functionality for TopoStats to accelerate the development of novel therapies and improve our understanding of health and disease.
Read more about the award here
In July 2023, Alice won the very prestigious AFM and SPM award presented by the Royal Microscopical Society. Alice has been an independent fellow since 2017 and has been at the University of Sheffield since 2019. Since starting her lab, she has taken the AFM field by storm whilst working closely with industry to develop new AFM methods, enabling us to observe the double helix of DNA at and conduct intricate experiments observing DNA-protein interactions. We’re all very proud of her!
Read about Alice’s award here!
Alice has been awarded a prestigious UKRI Future Leaders Fellowship in Round six of the scheme. Her fellowship “Unravelling the Invisible Complexities of the Genome” will support her ambitious aims of developing a new open biophysical pipeline, combining Atomic Force Microscopy and automated image analysis to determine how complex DNA structures within the genome affect essential cellular interactions. You can read the press release from Sheffield here.
Alice and Kavit along with collaborators from around the UK have published on, ‘Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides’
Isabel and Alice along with Prof. Rachel McKendry have published their paper, ‘Cantilever Sensors for Rapid Optical Antimicrobial Sensitivity Testing’ in ACS Sensors find the paper here: https://pubs.acs.org/doi/10.1021/acssensors.0c01216
The cover of the newly released (March 2018) ACS Synthetic Biology highlights our exciting collaborative research with UCL Chemistry and The National Physical Laboratory
New antibiotics are desperately needed: without them antimicrobial resistance is predicted to kill more people than cancer. An international collaboration between scientists at the London Centre for Nanotechnology (LCN), University of Oxford, IBM, STFC Daresbury Laboratory and the National Physical Laboratory (NPL) has shown that our own bodies may provide an answer.
DNA Origami Inside-Out Virus
This exciting new fellowship aims to create the future for international leaders in research.
Alice has featured in a high-profile webinar celebrating the 30th anniversary of the Nobel Prize in Scanning Tunnelling Microscopy (STM) and the 30th anniversary since the first paper in Atomic Force Microscopy (AFM)
Studies of G- Quadruplexes formed within self assembled DNA mini-circles.
