Our new research published today in Cell Reports gives new insights into how G-quadruplexes formed in the DNA of certain cancer cell lines can effect the way our immune system is able to respond to the disease. In collaboration with Shayla Mosley and Kristi Baker at the University of Alberta we discovered how the presence of G4s in the DNA which exists in the cytosol of cancer cells can stimulate the cGAS/STING pathway in our immune response, possibly leading to better outcomes. This work was supported by a University of Sheffield Global Partnership Development Fund Grant awarded to Thomas Catley.